Chronic Pain and Dopamine

February 8, 2020

Patients with chronic pain have a signaling mechanism, whether induced by medications or their endogenous pain, that causes them to seek out dopaminergic stimulation, to relieve their pain.

Some of these dopaminergic stimulation can be substituted by dietary intake.

Excessive nonnutritive dietary intake leads to obesity and visceral adipose tissue accumulation, which is inflammatory.

Excessive inflammatory mediators aggravate pain, and the cycle repeats.