Altered cholesterol metabolism in the brain may have a role in Alzheimer’s.

Summary: Accumulation of amyloid-beta appears to play a central role in the development of Alzheimer’s. However, researchers have a limited understanding of the production of amyloid protein in brain cells. But new studies show that the production of amyloid-beta protein is increased in those with higher cholesterol synthesis by astrocytes (supporting cells in the brain)… Continue reading Altered cholesterol metabolism in the brain may have a role in Alzheimer’s.

Does Chronic Over Nutrition Play A Role In Metabolic Inflammation?

We have been looking at metabolic inflammation and its role in the development of obesity, diabetes and other chronic diseases. Does overnutrition contribute to metabolic inflammation? How? Some background on overnutrition…. It is estimated that by 2020, two-thirds of the global burden of the disease will be due to chronic non-communicable diseases, most of which… Continue reading Does Chronic Over Nutrition Play A Role In Metabolic Inflammation?

How Effective Is The Carnivore Diet In Curbing Chronic Obesity?

Obesity has become rampant in recent times. It is said to affect almost 50% of the American population. It has been credited with being a leading cause of chronic illness and ill health. The carnivore diet has become very popular as the new way to lose weight, maintain a healthy lifestyle and ward off diseases.… Continue reading How Effective Is The Carnivore Diet In Curbing Chronic Obesity?

Metabolism Drive Inflammation

Cellular metabolic overactivity leads to metal inflammation. The immune system protects us from infections and tumors. the linkage between metabolism and inflammation, which seems clinically evident, has been elusive to demonstrate from a biochemical pathway perspective. Researchers demonstrated that the metabolic activity in the immune cells of primary immunodeficiency disorders (PID) patients is significantly up-regulated,… Continue reading Metabolism Drive Inflammation

Why Stressed People Can’t Seem to Lose Weight.

Mindset effects weight at a biochemical level. Clinically we tell patients that weight loss is about mindset, but I’ve struggled to explain the biochemical pathway why epinephrine associated with stress would cause insulin-resistant patients to gain weight, rather than lose weight. 1. Chronically elevated stress responses lead to elevated epinephrine. 2. Epinephrine normally signals for… Continue reading Why Stressed People Can’t Seem to Lose Weight.

Eating time and weight gain

Our eating patterns can influence insulin production and weight gain, and it’s important to give our bodies time to burn energy from food. Most people eat from the time they wake up until the time they go to bed — typically three main meals, multiple snacks, and often soda in between. This pattern leads to… Continue reading Eating time and weight gain

Time-Restricted Feeding

Time Restricted Feeding | Reverse Diabetes MD from Gurpreet Padda on Vimeo. Time-restricted feeding. Time-restricted feeding can help people move into a healthier lifestyle and reverse insulin resistance as well as maintain a healthy weight. Most people eat from the time they wake up until the time they go to bed; typically, they eat three… Continue reading Time-Restricted Feeding