Insulin is a vital hormone that controls the levels of sugar in our bodies. In a nutshell, it removes excess glucose from the blood through a process known as glycogenesis. However, problems with insulin are at the heart of many medical conditions. Insulin resistance occurs when your cells stop responding to insulin. This means that… Continue reading What Exactly Is Insulin Resistance?
Understanding the risk factors that could lead to prediabetes and diabetes type 2… • Weight: Being overweight (have a body mass index—a BMI—of higher than 25), increases your risk for developing prediabetes. This is especially true if you carry a lot of extra weight in your abdomen. The extra fat cells can cause your body… Continue reading What are Market for Developing Prediabetes and Type 2 Diabetes
The more insulin you have, the more fat you accumulate. Insulin activates the enzyme hexokinase, which phosphorylates glucose, trapping it within the cell, (and inhibits the activity of glucose-6-phosphatase, preventing phosphorylated glucose from being returned to glucose). Insulin also activates several of the enzymes that are directly involved in glycogen synthesis, including phosphofructokinase and glycogen… Continue reading Insulin is a Fat Storage Hormone
In the US, 52.3% of the adult population has either type 2 diabetes or prediabetes. Less than 12.2% of the adult population is metabolically healthy. Six feedings a day are a recipe for insulin resistance. Dietary carbs are only necessary if a person is currently taking diabetes medications associated with the risk for hypoglycemia such… Continue reading Prove Me Wrong.
Once the body is in nutritional ketosis, reduced insulin shifts the metabolic pathways to preferentially burn fat stores instead of storing fat stores. This leads to weight loss and can reverse the symptoms of diseases like Type 2 diabetes. Impaired glucose tolerance and type 2 diabetes mellitus are associated with increased risk of cardiovascular disease.… Continue reading The Cheat Day? Keto Diet and Metabolic Flexibility
Many people think that obesity isn’t treatable once they have reached a certain age, and thus have an indifferent attitude. I have patients in their 60s who tell me they are too old to reverse their obesity, and what difference would it make anyway? They assume that being overweight is an issue of how they… Continue reading It’s Never too Late to Reverse Obesity
The longer progression to Type 2 Diabetes can be delayed, even if using oral hypoglycemics, the more cost-effective it is. Most physicians wait until someone’s HgBA1C exceeds 6.5, but this is a mistake. The following is a cost analysis of early intervention with metformin, compared to delaying treatment until insulin supplementation is required due to… Continue reading Continuum of Type 2 Diabetes Progression
Our eating patterns can influence insulin production and weight gain, and it’s important to give our bodies time to burn energy from food. Most people eat from the time they wake up until the time they go to bed — typically three main meals, multiple snacks, and often soda in between. This pattern leads to… Continue reading Eating time and weight gain
Time-restricted feeding can reduce high insulin levels, which can reverse type 2 diabetes. It’s important to understand some facts about insulin and how it works. First, insulin is fat storage and a growth hormone. It reduces circulating glucose by converting it to glycogen storage first, which then overflows to fat storage. Eating carbohydrates causes insulin… Continue reading Time-Restricted Feeding
Can anxiety and depression unexpectedly improve when treating insulin resistance with metformin? I am an interventional pain physician in the urban core. More than 90% of my patients with chronic unrelenting pain also have metabolic syndrome with insulin resistance, and more than 90% also have significant anxiety and depression. I had always assumed that the… Continue reading Anxiety and Depression