Commonly used antidepressant changes the brain’s fat composition

Summary: Depression in children and young adults is on the rise. Depression-related suicides are among the leading causes of death among this age group. As a result, doctors are now more likely to prescribe antidepressants in this age group. Prozac (fluoxetine) is among the most used antidepressants in young adults. However, there are worries that… Continue reading Commonly used antidepressant changes the brain’s fat composition

The gut has a greater say in brain health than thought earlier

Summary: There is mounting evidence that the gut-brain axis plays a broader role in health. It also appears to have much influence on the brain health. The gut has more neurons than the spinal cord, producing numerous hormones, neurohormones, and neuropeptides. The gut produces 95% of serotonin. Additionally, the vagal nerve that innervates the gut… Continue reading The gut has a greater say in brain health than thought earlier

Obesity is an independent risk factor for depression

Summary: Metabolic disorders and depression are widespread. It is a well-established fact that obesity increases the risk of metabolic diseases like diabetes or cardiovascular conditions. Further, studies show that obesity also considerably increases the risk of depression. Although the relationship between obesity and metabolic disorders is quite clear, researchers are not sure how it increases… Continue reading Obesity is an independent risk factor for depression

PTSD

PTSD is a chronic condition that affects up to 12% of civilians and up to 30% of the veteran population. PTSD is associated with increased rates of type 2 diabetes, obesity, glucose dysregulation, inflammation, metabolic syndrome, and depression. This retrospective analysis of VA records from 2008 to 2015 identified 1,598 patients with PTSD and free… Continue reading PTSD

Anxiety and Depression

Can anxiety and depression unexpectedly improve when treating insulin resistance with metformin? I am an interventional pain physician in the urban core. More than 90% of my patients with chronic unrelenting pain also have metabolic syndrome with insulin resistance, and more than 90% also have significant anxiety and depression. I had always assumed that the… Continue reading Anxiety and Depression