Insulin Resistance and Chronic Pain

Important Points: Fibromyalgia Chronic pain hemoglobin A1c insulin resistance Insulin Resistance and Chronic Pain An estimated 10 million adults in the United States live with fibromyalgia — a condition that causes pain throughout the body often to the point where it’s difficult to function. Could the key to understanding and treating fibromyalgia and other chronic pain involve […]

Hyperinsulinemia Causing Chronic Pain – Gurpreet Padda: Episode 33

Dr. Gurpreet Padda is an interventional pain physician who treats patients with profound, chronic, severe pain that is unrelenting.  Over time he worked out that there was more to these people’s pain than just the physical source of it and that it was also a systemic or metabolic inflammatory issue and that hyperinsulinemia was at […]

Chronic Pain and Dopamine

Patients with chronic pain have a signaling mechanism, whether induced by medications or their endogenous pain, that causes them to seek out dopaminergic stimulation, to relieve their pain. Some of these dopaminergic stimulation can be substituted by dietary intake. Excessive nonnutritive dietary intake leads to obesity and visceral adipose tissue accumulation, which is inflammatory. Excessive […]

Could Chronic Pain Patients Be Could Substitution Sugar For Opioids….

Could sugar self-substitution for opioids in our patient’s be leading to insulin resistance, obesity, T2DM? In an experiment done on mini-pigs, they found that sugar can affect the brain’s reward system in a similar “manner similar to that of drugs of abuse” Sugar’s impact on the brain’s reward system boils down to how it affects […]

Dual Burden of Malnutrition Obesity Starvation

It is estimated that by 2020, two-thirds of the global burden of disease will be due to chronic non-communicable diseases, most of which are associated with diet. While hunger is a tremendous global health concern that cannot be minimized, overnutrition should similarly be given concentrated attention. Malnutrition affects up-to 1 billion people. Even though undernutrition […]

Addiction Model of Obesity: Its Dopamine Deficiency From Inflammation

An explanation why motivation is reduced with metainflammation and a possible explanation why many patients with diabetes develop chronic pain pathologies with anhedonia, reflections on the addiction model of obesity. The brain’s dopamine system, which drives motivation, is directly affected by chronic, low-grade inflammation. If your brain perceives that it is fighting off an infection […]

Insulin Resistance is an Unrecognized Cause of Chronic Pain.

Your pain physician should be addressing obesity and insulin resistance if they hope to ever reverse your pain. Metabolic inflammation (metainflammation) of obesity and hyperinsulinemia is an under-recognized cause of pain in the United States. Musculoskeletal pain has been estimated to affect 13.5%–47% of the general population, and 75 percent of those affected have two […]