In this LowCarbUSA podcast episode, Dr. Gurpreet Singh Padda, MD, MBA, MHP, explains how hyperinsulinemia causes chronic pain. Hyperinsulinemia means too much insulin in the blood. That excess insulin fuels a whole-body, metabolic inflammation that sits under the physical source of the pain. The standard American diet sets it off: vegetable oils, processed carbs and excess sugar.
Dr. Padda is an interventional pain physician. He treats patients with deep, chronic, severe pain that does not let up. Over time he saw that there was more to their pain than its physical source. It was also a systemic, metabolic inflammatory problem, and hyperinsulinemia was at the root of it. He found that most of his patients were obese and either pre-diabetic or diabetic. He found that most of them also had leaky gut.
All of this was caused by the standard American diet (SAD): vegetable oils, processed carbs and too much sugar. He talks about how the junk food companies push the fructose level higher than regular high fructose corn syrup. They do it to make the food more addictive.
What he is doing in the community is astounding. They have over 65,000 active patients in their online program, which is totally free. He even puts more than a million dollars of his own money into the program every year.
You can find out more about this program at:
https://reversingdiabetesmd.com/
Related reading
- Ketogenic Diet Show Interview
- Hyperinsulinemia Causing Chronic Pain
- Episode 91: Dr. Gurpreet Padda on Metabolic Inflammation
- Episode 79: Dr. Padda’s Frightening Health Information
- Dr. Padda on Bethalto Today radio
Medically reviewed by Dr. Gurpreet Singh Padda, MD, MBA, MHP
Interventional pain physician, addiction medicine specialist and obesity medicine diplomate.
Licensed in Missouri and Illinois.
Last reviewed June 4, 2026
