Metabolic Signals And Innate Immune Activation In Obesity

The interplay between immunity, inflammation, and metabolic changes is a growing field of research. Exciting new evidence is emerging with regard to their role in the regulation of metabolism and the activation of inflammatory pathways during the progression of metabolic disorders such as Type 2 Diabetes and Atherosclerosis. The innate immune system The innate immune system […]

Autism Rates Increasing, With Soybean Oil Consumption.

Soybean oil is the most widely produced and consumed edible oil in the U.S., consumption dramatically increased right before the beginnings of the 1970’s. In the 1970s and 1980s, about 1:2,000 children had autism. Today, the CDC estimates that 1:150 has an autism spectrum disorder or ASD. A True Increase or Semantics? More to come, […]

50 g of Pre-Operative Carbohydrate Loading?

ENSURE PRE-SURGERY is specially designed to help reduce insulin resistance after surgery and improve patient outcomes. Designed to be consumed up to 2 hours before surgery. For oral use. Use under medical supervision. • #1 Doctor recommended brand. • Has a recommended dose of carbohydrates (50 g per serving), as indicated by ERAS guidelines*, compared to regular […]

Rats, Food, Prisons – Reversing The Diabetes Pandemic With Dr. Gurpreet Padda

We are living in a diabetes pandemic. But diabetes isn’t just about blood sugar, it’s systemic inflammation, incessant cravings-driven eating. It’s obesity. And it’s impacting our nation in ways most are completely unaware of. From our children’s exposure to the U.S. dietary regulations in our public schools and the rise in ADD (Attention Deficit Disorder), […]

The Missing Link; Dopamine, Obesity, Metainflammation, Diabetes Type 2

Nearly 77% of the US population is now overweight. This dramatic change in the last 50 years is correlated with the availability of highly processed foods, and with a dramatic increase in chronic pain. In a mouse model, high-calorie foods, which induces a dopamine release, disrupted normal feeding schedules, resulting in overconsumption. Additionally, the “knockout” […]

Could Chronic Pain Patients Be Could Substitution Sugar For Opioids….

Could sugar self-substitution for opioids in our patient’s be leading to insulin resistance, obesity, T2DM? In an experiment done on mini-pigs, they found that sugar can affect the brain’s reward system in a similar “manner similar to that of drugs of abuse” Sugar’s impact on the brain’s reward system boils down to how it affects […]

Inflammatory Cytokines From Fat Tissue

Adipose tissue-derived proteins known to affect inflammation TNF-α IL-6 IL-1β Leptin Adiponectin Resistin Acylation-stimulating protein SAA3 α1 acid glycoprotein Pentraxin-3 IL-1 receptor antagonist Macrophage migration inhibitory factor.

Metabolic Inflammation As A Cause Of Insulin Resistance

In previous articles, I have discussed the role of metabolic Inflammation in obesity and diabetes. Today, we will narrow down to the specifics of what insulin resistance is, its effects and how metabolic inflammation increases the chances of one developing it. What is Insulin resistance? Approximately 30% of Americans, and up to 50% in the […]

What Is The Relationship Between Metabolic Inflammation And Type 2 Diabetes?

A growing body of data shows that type 2 diabetes is at least in part rooted in inflammation. The higher a person’s body mass index, the more pro-inflammatory macrophages they have in their adipose tissue, and the higher their chances of developing T2D. In this article, we will highlight the emerging role of inflammation in […]

Metabolic Inflammation: What Is It?

The modern diet contains a large number of simple sugars. From bread to donuts, to carbonated drinks to chocolate, cookies, and candy, everywhere you look, temptation abounds. The potential impact on the health of diets rich in free sugars, and particularly fructose, is of major concern. Does the sugar we take have an impact on […]