Mindset effects weight at a biochemical level. Clinically we tell patients that weight loss is about mindset, but I’ve struggled to explain the biochemical pathway why epinephrine associated with stress would cause insulin-resistant patients to gain weight, rather than lose weight. 1. Chronically elevated stress responses lead to elevated epinephrine. 2. Epinephrine normally signals for… Continue reading Why Stressed People Can’t Seem to Lose Weight.