Dopamine

Compulsive overeating is a more classically recognized addiction disorder. Dopamine is the recognized neurotransmitter for the classic substance abuse disorders and in the regulation of food reward and the hedonic aspects of appetite.

Episode 91: Dr. Gurpreet Padda

Today we are joined by Dr. Gurpreet Padda, a man of great learning and with a great interest in metabolic health and nutrition. He became interested in metabolic health when he noticed that, working in adult pain at the time, 91% of his patients were overweight. Through observation and experimentation, he noticed that metabolic inflammation […]

Sugar, Addiction, and Obesity

Sugar addiction, especially glucose, leads to obesity because of how it is metabolized. Sucrose (table sugar) is a disaccharide made of 50% fructose and 50% glucose. Sucrose is metabolized primarily in the small intestine, releasing equal parts glucose and fructose. Glucose causes insulin release and is rapidly cleared from the bloodstream by insulin-dependent channels. Fructose […]

Addiction, Obesity & Hyperpalatability

Foods made to taste exceptionally good (hyperpalatable) through combining high fat and high sugar can also lead to behavioral addiction, which can lead to obesity. Hyperpalatable foods can produce an addiction‐like syndrome. Animals presented with either high‐sugar or high‐fat diets eat excessively but do not gain weight as they offset the increased intake by eating […]